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Chromosome 13 : ウィキペディア英語版
Chromosome 13 (human)

Chromosome 13 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 13 spans about 114 million base pairs (the building material of DNA) and represents between 3.5 and 4% of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the number of genes varies. Chromosome 13 likely contains between 300 and 700 genes.
==Genes==
The following are some of the genes located on chromosome 13:
* ATP7B: ATPase, Cu++ transporting, beta polypeptide (Wilson disease)
* BRCA2: breast cancer 2, early onset
* CARKD: Carbohydrate Kinase Domain Containing Protein (Unknown Function)
* EDNRB: endothelin receptor type B
* GJB2: gap junction protein, beta 2, 26kDa (connexin 26)
* GJB6: gap junction protein, beta 6 (connexin 30)
* HTR2A: 5-HT2A receptor
* PCCA: propionyl Coenzyme A carboxylase, alpha polypeptide
* RB1: retinoblastoma 1 (including osteosarcoma)
* FLT1: Fms related tyrosine kinase 1 (Vascular endothelial growth factor receptor 1)
* SLITRK1: mutation in this gene causes some (although very few) cases of Tourette syndrome and trichotillomania
* SOX21: Transcription factor SOX-21 is a protein that in humans is encoded by the SOX21; its disruption can lead to types of alopecia in mice.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Chromosome 13 (human)」の詳細全文を読む



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